Angiogenic Monocytes

Angiogenic Activity Monocytes to Increase Expression of Non-Small Cell Lung Cancer Cells Induce

On-site education of VEGF-recruited monocytes improves their performance as angiogenic and arteriogenic accessory cells

Adult neovascularization relies on the recruitment of monocytes to the target organ or tumor and functioning therein as a paracrine accessory. The exact origins of the recruited monocytes and the mechanisms underlying their plasticity remain unclear. Using a VEGF-based transgenic system in which genetically tagged monocytes are conditionally summoned to the liver as part of a VEGF-initiated ang...

From Human Monocytes Factor Production and Angiogenic Activity M-CSF Induces Vascular Endothelial Growth

Differentiation of Monocytes to Macrophages The Novel Angiogenic Inhibitor, Angiocidin, Induces

We previously showed that angiocidin, a tumor and vascular associated protein, is a potent inhibitor of angiogenesis and tumor growth. Angiocidin is a multidomain protein that exerts its antiangiogenic activity through multiple mechanisms, including effects on cell matrix interaction. Here, we describe another activity of angiocidin that may contribute to its antitumor activity. We show that an...

The novel angiogenic inhibitor, angiocidin, induces differentiation of monocytes to macrophages.

We previously showed that angiocidin, a tumor and vascular associated protein, is a potent inhibitor of angiogenesis and tumor growth. Angiocidin is a multidomain protein that exerts its antiangiogenic activity through multiple mechanisms, including effects on cell matrix interaction. Here, we describe another activity of angiocidin that may contribute to its antitumor activity. We show that an...